Clinical Manifestations, Treatment, and Prevention of Acute Irritant Contact Dermatitis Caused by 2,4-Dichloro-5-Methylpyrimidine

Ichthyosiform Irritant Contact Dermatitis Caused by Antiseptics for Personal Hygiene

Background: Antiseptics are commonly used for personal hygiene in Taiwan. We have previously reported a series of ichthyosiform irritant contact dermatitis induced by cetrimide-containing antiseptics. Objectives: To report a new series of antiseptics-induced ichthyosiform irritant contact dermatitis and bring attention to the potential irritation effects of antiseptics. Methods: We reviewed the...

Allergic and Irritant Contact Dermatitis

Perfluoropolyethers in the prevention of irritant contact dermatitis.

BACKGROUND Perfluoropolyethers (PFPEs) are non-reactive perfluorinated (no hydrogen atoms) liquid polymers that showed promise as ingredients of protective preparations in occupational dermatology. OBJECTIVE The aim of this study was to investigate if oil-in-water (o/w) emulsions containing 0.5, 1.0, 2.0 and 4.0% PFPEs (molecular weight 6,250 D) prevent epidermal barrier disruption induced by...

Severe acute irritant contact dermatitis presenting as exfoliative erythroderma.

Conflicts of interest: The authors have declared no conflicts. hands, legs below knee level, and the area between the shoulder blades (Fig. 1). The patient had no history of dermatological disease and no prior or present exposure to sunlight, infection, or drugs. Biochemical screening was normal, skin cultures were negative, and a biopsy from lesional skin showed changes compatible with dermati...

Cytokines and Chemokines in Irritant Contact Dermatitis

Irritant contact dermatitis is a result of activated innate immune response to various external stimuli and consists of complex interplay which involves skin barrier disruption, cellular changes, and release of proinflammatory mediators. In this review, we will focus on key cytokines and chemokines involved in the pathogenesis of irritant contact dermatitis and also contrast the differences bet...